Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448847 | 0.91 | FFAR4 (0.43) | FFAR4L3MBTL1TDP1HTTLMNA | |
| SCHEMBL11081800 | 0.85 | TDP1 (0.47) | L3MBTL1TDP1HTTLMNASMN1; SMN2 | |
| SCHEMBL11624067 | 0.84 | ALDH1A1 (0.47) | FFAR4TDP1HTTSMN1; SMN2GAA | |
| SCHEMBL11852879 | 0.83 | MEN1 (0.56) | L3MBTL1TDP1HTTLMNASMN1; SMN2 | |
| SCHEMBL11844234 | 0.83 | TDP1 (0.62) | FFAR4L3MBTL1TDP1HTTLMNA | |
| SCHEMBL11841583 | 0.81 | GAA (0.47) | L3MBTL1TDP1HTTLMNASMN1; SMN2 | |
| SCHEMBL11848172 | 0.80 | TDP1 (0.57) | L3MBTL1TDP1HTTLMNASMN1; SMN2 | |
| SCHEMBL11091725 | 0.80 | CA2 (0.46) | FFAR4L3MBTL1TDP1HTTLMNA | |
| SCHEMBL10652647 | 0.80 | CA12 (0.47) | L3MBTL1TDP1HTTLMNASMN1; SMN2 | |
| SCHEMBL11841874 | 0.79 | TDP1 (0.56) | L3MBTL1TDP1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996368-A | Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |