SCHEMBL11624201

SCHEMBL11624201

CCN(CC)C(C)OC(=O)CNC(=S)C(C)Cc1nc(-c2ccccc2)no1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
GAA P10253 2/20 0.46
TSHR P16473 5/20 0.44
HTT P42858 3/20 0.43
HPGD P15428 2/20 0.43
MAPK1 P28482 4/20 0.41
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
HIF1A Q16665 1/20 0.41
HTR1A P08908 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 3/20 0.40
LMNA P02545 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11624400 0.91 TSHR (0.45) ALDH1A1GAATSHRHTTHPGD
SCHEMBL11624556 0.85 KMT2A (0.50) ALDH1A1GAATSHRHTTHPGD
SCHEMBL11628331 0.83 ALDH1A1 (0.53) ALDH1A1GAATSHRHTTHPGD
SCHEMBL11628337 0.83 ALDH1A1 (0.53) ALDH1A1GAATSHRHTTHPGD
Potassium Ion SCHEMBL11624299 0.80 ALDH1A1 (0.50) ALDH1A1GAATSHRHTTHPGD
Potassium Ion SCHEMBL11624303 0.80 ALDH1A1 (0.50) ALDH1A1GAATSHRHTTHPGD
Trolamine SCHEMBL11629192 0.78 ALDH1A1 (0.46) ALDH1A1GAATSHRHTTMAPK1
Monoethanolamine SCHEMBL11629191 0.78 ALDH1A1 (0.47) ALDH1A1GAATSHRHTTHPGD
SCHEMBL11625604 0.72 NOTUM (0.58) ALDH1A1GAATSHRHTTMAPK1
SCHEMBL11624561 0.72 MEN1 (0.48) ALDH1A1GAATSHRHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4067988-A 3-Phenyl-1,2,4-oxadiazole derivatives as antiinflammatory-antitussive agents LABORATOIRES CASSENNE (FR) 1978-01-10 US disclosed