Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620572 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL11620129 | 0.83 | MEN1 (0.48) | MEN1KMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL11620226 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL11622461 | 0.80 | KMT2A (0.48) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL11619273 | 0.76 | HPGD (0.43) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL11620712 | 0.75 | CARM1 (0.42) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL2917221 | 0.72 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL11616005 | 0.71 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1LMNANPC1 | |
| Hydrochloric Acid SCHEMBL11626361 | 0.71 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL11621243 | 0.69 | RAB9A (0.36) | MEN1KMT2AALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |