Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 13/20 | 0.48 |
| ▸ | PDE1A | P54750 | 5/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297225 | 0.90 | PDE5A (0.55) | PDE5APDE1APDE1BPDE1CPDE10A | |
| SCHEMBL11626599 | 0.89 | MEN1 (0.51) | PDE5APDE1APDE1BPDE1CPDE10A | |
| SCHEMBL7940546 | 0.89 | GUSB (0.58) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11624834 | 0.87 | PARP1 (0.56) | GUSBKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL11624915 | 0.87 | PDE5A (0.46) | GUSBPDE5A | |
| SCHEMBL11707366 | 0.86 | GUSB (0.53) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11628793 | 0.86 | KDM4E (0.57) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11711295 | 0.86 | GUSB (0.53) | GUSBPDE5APDE1APDE1BPDE1C | |
| Potassium Ion SCHEMBL11709053 | 0.86 | GUSB (0.53) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11629646 | 0.85 | IDO1 (0.47) | PDE5ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |