Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 13/20 | 0.47 |
| ▸ | PDE1A | P54750 | 5/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628793 | 0.90 | KDM4E (0.57) | GUSBKDM4EALDH1A1PDE5APDE1A | |
| SCHEMBL7940546 | 0.88 | GUSB (0.58) | GUSBKDM4EALDH1A1PDE5APDE1A | |
| SCHEMBL11624906 | 0.86 | GUSB (0.54) | GUSBKDM4EALDH1A1PDE5APDE1A | |
| Potassium Ion SCHEMBL11709053 | 0.85 | GUSB (0.53) | GUSBKDM4EALDH1A1PDE5APDE1A | |
| SCHEMBL11711295 | 0.85 | GUSB (0.53) | GUSBKDM4EALDH1A1PDE5APDE1A | |
| SCHEMBL8294627 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9296772 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1PDE5APDE1APDE1B | |
| SCHEMBL11628682 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1PDE5APDE1APDE1B | |
| SCHEMBL11628488 | 0.81 | KDM4E (0.53) | GUSBKDM4EALDH1A1 | |
| SCHEMBL11628765 | 0.81 | KDM4E (0.53) | GUSBKDM4EALDH1A1PDE5AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031093-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |