Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.58 |
| ▸ | PDE5A | O76074 | 11/20 | 0.49 |
| ▸ | PDE1A | P54750 | 5/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295923 | 0.90 | PDE5A (0.57) | PDE5APDE1APDE1BPDE1CPDE10A | |
| SCHEMBL11710197 | 0.89 | PDE5A (0.54) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11624906 | 0.89 | GUSB (0.54) | GUSBPDE5APDE1APDE1BPDE1C | |
| Potassium Ion SCHEMBL11709053 | 0.88 | GUSB (0.53) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11711295 | 0.88 | GUSB (0.53) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11707366 | 0.88 | GUSB (0.53) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11628793 | 0.88 | KDM4E (0.57) | GUSBPDE5APDE1APDE1BPDE1C | |
| SCHEMBL11707410 | 0.86 | PDE5A (0.47) | GUSBPDE5A | |
| SCHEMBL11629702 | 0.84 | KDM6B (0.44) | GUSBPDE5A | |
| SCHEMBL11711629 | 0.84 | GAA (0.45) | GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239136-B1 | REGULATING APOPTOSIS IN HUMAN CELLS HAVING AUTOIMMUNE DISEASE | CELL PATHWAYS, INC. | 2001-05-29 | — | — | US | disclosed |
| US-5874440-A | ADMINISTERING TO THE PATIENT HAVING PRECANCEROUS LESIONS TO INHIBIT GROWTH OF NEOPLASTIC CELLS | CELL PATHWAYS, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| US-4209623-A | ANTIASTHMA | BRISTOL-MYERS COMPANY (US) | 1980-06-24 | — | — | US | disclosed |
| US-4031093-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |