Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953685 | 0.82 | TLR8 (0.46) | TLR8TLR7L3MBTL1CYP1A2CYP2C19 | |
| Bupirimate SCHEMBL29394855 | 0.78 | TLR8 (0.33) | TLR8TLR7L3MBTL1CYP1A2CYP2C19 | |
| Bupirimate SCHEMBL22961 | 0.78 | TLR8 (0.33) | TLR8TLR7L3MBTL1CYP1A2CYP2C19 | |
| Bupirimate SCHEMBL29177491 | 0.77 | TLR8 (0.32) | TLR8TLR7L3MBTL1CYP1A2CYP2C19 | |
| Bupirimate SCHEMBL6008749 | 0.77 | TLR8 (0.32) | TLR8TLR7L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL11621518 | 0.74 | LMNA (0.46) | TLR8TLR7CYP1A2CYP2C19LMNA | |
| Ethirimol SCHEMBL20692 | 0.74 | TLR8 (0.41) | TLR8TLR7L3MBTL1CYP1A2CYP2C19 | |
| Ethirimol SCHEMBL8818899 | 0.74 | TLR8 (0.41) | TLR8TLR7L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL11624068 | 0.68 | KDM4E (0.50) | TLR8TLR7CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL27702560 | 0.67 | ALDH1A1 (0.42) | TLR8TLR7CYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116674-A | Process of severely damaging or killing unwanted plants with pyrimidine compounds | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |