Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HPSE | Q9Y251 | 12/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694832 | 0.85 | S1PR1 (0.53) | KDRTP53THRBHPSEKDM4E | |
| SCHEMBL5641287 | 0.84 | TP53 (0.56) | KDRTP53THRBKDM4ENPC1 | |
| Methane SCHEMBL11696301 | 0.84 | S1PR1 (0.52) | KDRTP53THRBHPSEKDM4E | |
| SCHEMBL507169 | 0.83 | KDM4E (0.77) | KDRHPSEKDM4ENPC1RAB9A | |
| SCHEMBL10877092 | 0.82 | KDM4E (0.59) | HPSEKDM4EALDH1A1MAPTGAA | |
| SCHEMBL5640210 | 0.82 | TP53 (0.56) | KDRTP53THRBKDM4ENPC1 | |
| SCHEMBL6614228 | 0.81 | HPSE (0.55) | HPSEKDM4EGAA | |
| SCHEMBL9820079 | 0.80 | HPSE (0.72) | TP53HPSEKDM4ESMN1; SMN2MAPT | |
| Methane SCHEMBL506232 | 0.79 | HPSE (0.70) | TP53HPSEKDM4ESMN1; SMN2MAPT | |
| SCHEMBL9115528 | 0.77 | ESR1 (0.65) | KDRTP53THRBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087437-A | FORMATION OF AMMONIUM SALT THEREOF, THERMALLY RECONVERTING SALT TO THE ACID | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |