Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 15/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL506232 | 0.99 | HPSE (0.70) | HPSEKDM4EMAPTGAATP53 | |
| SCHEMBL507169 | 0.88 | KDM4E (0.77) | HPSEKDM4EGAASMN1; SMN2 | |
| SCHEMBL11626342 | 0.87 | HPSE (0.72) | HPSEKDM4EMAPTGAASMN1; SMN2 | |
| SCHEMBL5461475 | 0.87 | HPSE (0.72) | HPSEKDM4EMAPTGAATP53 | |
| SCHEMBL14581706 | 0.86 | HPSE (0.70) | HPSEKDM4EGAA | |
| Methane SCHEMBL505763 | 0.86 | HPSE (0.70) | HPSEKDM4EMAPTGAASMN1; SMN2 | |
| Methane SCHEMBL5476423 | 0.86 | HPSE (0.70) | HPSEKDM4EMAPTGAATP53 | |
| Methane SCHEMBL25304065 | 0.85 | HPSE (0.69) | HPSEKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL20515142 | 0.84 | HPSE (1.00) | HPSEKDM4E | |
| SCHEMBL5641397 | 0.83 | MAPT (0.55) | HPSEKDM4EMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182061-B1 | NEW PROCESS FOR PREPARING 2(4-FLUOROPHENYL) ALPHA METHYL-5-BENZOXAZOLE ACETIC ACID | RAVIZZA S.p.A. (IT) | 1991-12-27 | — | — | EP | claimed |
| US-4652654-A | Process for preparing 2(4-fluorophenyl)alpha-methyl-5-benzoxazole acetic acid | RAVIZZA SPA (IT) | 1987-03-24 | — | — | US | claimed |
| EP-0182061-A1 | New process for preparing 2(4-fluorophenyl) alpha methyl-5-benzoxazole acetic acid | RAVIZZA S.p.A. (IT) | 1986-05-28 | — | — | EP | claimed |
| EP-0182061-B1 | NEW PROCESS FOR PREPARING 2(4-FLUOROPHENYL) ALPHA METHYL-5-BENZOXAZOLE ACETIC ACID | RAVIZZA S.p.A. (IT) | 1991-12-27 | — | — | EP | disclosed |
| US-4652654-A | Process for preparing 2(4-fluorophenyl)alpha-methyl-5-benzoxazole acetic acid | RAVIZZA SPA (IT) | 1987-03-24 | — | — | US | disclosed |
| US-4652654-A | Process for preparing 2(4-fluorophenyl)alpha-methyl-5-benzoxazole acetic acid | RAVIZZA SPA (IT) | 1987-03-24 | — | — | US | disclosed |
| EP-0182061-A1 | New process for preparing 2(4-fluorophenyl) alpha methyl-5-benzoxazole acetic acid | RAVIZZA S.p.A. (IT) | 1986-05-28 | — | — | EP | disclosed |
| EP-0182061-A1 | New process for preparing 2(4-fluorophenyl) alpha methyl-5-benzoxazole acetic acid | RAVIZZA S.p.A. (IT) | 1986-05-28 | — | — | EP | disclosed |