Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829496 | 0.88 | CYP1A2 (0.81) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA | |
| SCHEMBL5444784 | 0.88 | RAB9A (0.66) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA | |
| SCHEMBL6502794 | 0.87 | RAB9A (0.66) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA | |
| SCHEMBL11625714 | 0.86 | CYP1A2 (1.00) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA | |
| SCHEMBL11828419 | 0.84 | CYP1A2 (0.74) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA | |
| SCHEMBL166484 | 0.82 | LMNA (0.82) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA | |
| SCHEMBL3006426 | 0.82 | RAB9A (0.71) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA | |
| SCHEMBL21768049 | 0.81 | LMNA (0.76) | KMT2AL3MBTL1LMNANPC1POLB | |
| Hydrochloric Acid SCHEMBL27843329 | 0.81 | LMNA (0.80) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA | |
| SCHEMBL11836444 | 0.81 | CYP1A2 (0.70) | CYP1A2CYP3A4KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553491-B | Quinoxaline derivative | ASKA PHARM CO LTD | 2013-05-29 | — | — | CN | disclosed |
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |