Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | ICMT | O60725 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11901010 | 0.89 | LMNA (0.69) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10969527 | 0.85 | KDM4E (0.72) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11862075 | 0.83 | POLB (0.68) | LMNARAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9704955 | 0.81 | LMNA (0.59) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL19019393 | 0.81 | TP53 (0.69) | HDAC6 | |
| SCHEMBL11132798 | 0.81 | HDAC4 (0.63) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31091436 | 0.81 | HDAC3 (0.78) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14483841 | 0.81 | HDAC3 (0.78) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11864941 | 0.81 | LMNA (0.62) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11628083 | 0.80 | TP53 (0.50) | KDM4EMEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067726-A | 3-Ureido phenylacetamide herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | claimed |