Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969527 | 0.95 | KDM4E (0.72) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9704955 | 0.91 | LMNA (0.59) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14483841 | 0.90 | HDAC3 (0.78) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31091436 | 0.90 | HDAC3 (0.78) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11132798 | 0.90 | HDAC4 (0.63) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11864941 | 0.90 | LMNA (0.62) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11627440 | 0.89 | LMNA (0.58) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL19501814 | 0.89 | SOAT2 (0.68) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8388528 | 0.89 | HDAC4 (0.65) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11638630 | 0.89 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377530-B2 | Polyesters with low molecular weight additives for improved gas barrier properties | EASTMAN CHEMICAL COMPANY (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120199515-A1 | POLYESTERS WITH LOW MOLECULAR WEIGHT ADDITIVES FOR IMPROVED GAS BARRIER PROPERTIES | EASTMAN CHEMICAL COMPANY (US) | 2012-08-09 | — | — | US | disclosed |