Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22890934 | 0.95 | HDAC2 (0.48) | ACHECYP2C19MEN1KMT2AL3MBTL1 | |
| SCHEMBL22281737 | 0.91 | ALDH1A1 (0.53) | MEN1KMT2AL3MBTL1GLAKDM4E | |
| SCHEMBL25659999 | 0.90 | MEN1 (0.57) | ACHEMEN1KMT2AL3MBTL1GLA | |
| SCHEMBL2759481 | 0.88 | TDP1 (0.57) | CYP3A4TDP1ALDH1A1 | |
| SCHEMBL14173453 | 0.84 | CARM1 (0.40) | ACHEMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL20363766 | 0.80 | ALDH1A1 (0.53) | ACHEL3MBTL1GLAKDM4EALDH1A1 | |
| SCHEMBL28997919 | 0.79 | ALDH1A1 (0.45) | ACHECYP2C19MEN1KMT2ATDP1 | |
| SCHEMBL29834112 | 0.79 | ACHE (0.54) | ACHEKMT2AL3MBTL1GLAALDH1A1 | |
| SCHEMBL22861375 | 0.79 | ALDH1A1 (0.61) | KDM4EALDH1A1 | |
| SCHEMBL25279192 | 0.77 | CACNA1H (0.56) | MEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093615-A | Cyclic oligomers of N-substituted aziridines | THE DOW CHEMICAL COMPANY (US) | 1978-06-06 | — | — | US | disclosed |