Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 2/20 | 0.42 |
| ▸ | SELE | P16581 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667950 | 0.88 | MEN1 (0.39) | CYP1A2CYP2C19ALDH1A1 | |
| 3-Chloroaniline SCHEMBL11667345 | 0.87 | SIGMAR1 (0.40) | CYP1A2CYP2C19ALDH1A1SIGMAR1PTGDR2 | |
| SCHEMBL11626363 | 0.85 | LMNA (0.57) | AKR1B1CYP1A2CYP2C19SELPSELE | |
| SCHEMBL8953672 | 0.83 | HDAC1 (0.43) | HDAC1HDAC6LMNAALDH1A1GAA | |
| SCHEMBL11630909 | 0.82 | CA1 (0.46) | HDAC1HDAC6LMNAALDH1A1 | |
| SCHEMBL2553049 | 0.80 | KMT2A (0.54) | AKR1B1CYP1A2CYP2C19HDAC1HDAC6 | |
| SCHEMBL11628080 | 0.80 | HPGD (0.48) | HDAC1HDAC6LMNAALDH1A1GAA | |
| SCHEMBL11039869 | 0.79 | LMNA (0.42) | LMNAKDM4EPOLB | |
| SCHEMBL11627435 | 0.79 | TRPV1 (0.50) | HDAC1HDAC6GAAHPGD | |
| SCHEMBL20313977 | 0.77 | LMNA (0.49) | HDAC1HDAC6LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067726-A | 3-Ureido phenylacetamide herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | claimed |