Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 12/20 | 0.73 |
| ▸ | CES1 | P23141 | 11/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445781 | 0.90 | CES2 (0.71) | CES2CES1MAPTRAB9ALMNA | |
| Benzoyl Formic Acid SCHEMBL6550783 | 0.85 | CES2 (0.73) | CES2CES1MAPTRAB9ALMNA | |
| SCHEMBL180411 | 0.84 | CES2 (1.00) | CES2CES1MAPTRAB9ALMNA | |
| SCHEMBL15180810 | 0.84 | CES2 (1.00) | CES2CES1MAPTRAB9ALMNA | |
| Benzil SCHEMBL1481339 | 0.84 | CES2 (0.80) | CES2CES1MAPTRAB9ALMNA | |
| SCHEMBL5243256 | 0.82 | CES2 (0.95) | CES2CES1MAPTRAB9ALMNA | |
| Water SCHEMBL17802791 | 0.82 | CES2 (0.95) | CES2CES1MAPTRAB9ALMNA | |
| Benzil SCHEMBL4814635 | 0.81 | CES2 (0.82) | CES2CES1MAPTRAB9ALMNA | |
| Benzil SCHEMBL2252919 | 0.81 | CES2 (0.82) | CES2CES1MAPTRAB9ALMNA | |
| SCHEMBL5899450 | 0.81 | CES2 (0.60) | CES2CES1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071527-A | Certain benzothiazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-31 | — | — | US | disclosed |