Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829099 | 0.79 | SORT1 (0.49) | KCNMA1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11838491 | 0.77 | MEN1 (0.56) | TP53NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL30417052 | 0.75 | MEN1 (0.63) | TP53NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL27486980 | 0.75 | MEN1 (0.63) | TP53NPC1RAB9ASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL30416887 | 0.74 | MEN1 (0.61) | TP53NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11827383 | 0.72 | SORT1 (0.58) | TP53NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL27489099 | 0.72 | MEN1 (0.52) | KCNMA1TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL11727000 | 0.72 | F2R (0.53) | TP53ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8616448 | 0.72 | TP53 (0.65) | KCNMA1TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL11833252 | 0.72 | NPC1 (0.60) | TP53ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093734-A | ANTIULCER AGENTS, ANTIEMETICS, ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1978-06-06 | — | — | US | disclosed |