Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.52 |
| ▸ | PDE5A | O76074 | 4/20 | 0.47 |
| ▸ | MAP2 | P11137 | 2/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666113 | 0.90 | CAMKK2 (0.42) | IRAK4PDE5AMAP2CAMKK2PARP1 | |
| SCHEMBL11708696 | 0.89 | PDE5A (0.51) | IRAK4PDE5AALOX15HSD17B10 | |
| SCHEMBL11628832 | 0.89 | PARP1 (0.39) | IRAK4PDE5AALOX15PARP1HTT | |
| SCHEMBL11624834 | 0.86 | PARP1 (0.56) | CAMKK2ALOX15HSD17B10PARP1SLC9A1 | |
| SCHEMBL11624915 | 0.86 | PDE5A (0.46) | PDE5APARP1HTT | |
| SCHEMBL11624906 | 0.84 | GUSB (0.54) | PDE5AHSD17B10 | |
| SCHEMBL11628474 | 0.84 | KDM4E (0.53) | PDE5A | |
| SCHEMBL9297225 | 0.82 | PDE5A (0.55) | PDE5AALOX15HSD17B10 | |
| SCHEMBL11626599 | 0.81 | MEN1 (0.51) | PDE5AALOX15 | |
| SCHEMBL11629646 | 0.80 | IDO1 (0.47) | PDE5APARP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |