Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.86 |
| ▸ | PKM | P14618 | 6/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203532 | 0.92 | PKM (0.88) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL3303527 | 0.92 | PKM (0.88) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL3971438 | 0.92 | PKM (0.88) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL4537086 | 0.92 | PKM (0.88) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL10724066 | 0.92 | PKM (0.88) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL699639 | 0.92 | PKM (0.88) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL8200466 | 0.92 | PKM (0.88) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL565301 | 0.92 | PKM (0.88) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL10722295 | 0.88 | KMT2A (0.84) | GAAPKMHTTPOLBALDH1A1 | |
| SCHEMBL3830424 | 0.88 | POLB (0.80) | GAAPKMPOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087425-A | N,N-Disulfonylpiperazines | LABORATORIOS LIADE, S.A. (ES) | 1978-05-02 | — | — | US | disclosed |