Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 5/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628836 | 0.90 | NUDT1 (0.38) | KDM4EMEN1MAPTKMT2AHDAC4 | |
| SCHEMBL11342049 | 0.84 | KDM4E (0.39) | KDM4EMEN1MAPTKMT2AHDAC4 | |
| SCHEMBL11609703 | 0.84 | KDM4E (0.36) | KDM4EMEN1MAPTKMT2AHDAC4 | |
| SCHEMBL14702180 | 0.84 | KDM4E (0.42) | KDM4EMEN1MAPTKMT2AHDAC4 | |
| SCHEMBL2088699 | 0.84 | KDM4E (0.44) | KDM4EMEN1MAPTKMT2AHDAC4 | |
| SCHEMBL12161247 | 0.83 | NUDT1 (0.41) | KDM4EMEN1MAPTKMT2AHDAC4 | |
| SCHEMBL11799540 | 0.82 | KMT2A (0.47) | KDM4EMEN1MAPTKMT2AHDAC4 | |
| SCHEMBL39261 | 0.82 | KMT2A (0.47) | KDM4EMEN1MAPTKMT2AHDAC4 | |
| SCHEMBL17446312 | 0.81 | KDM4E (0.41) | KDM4EMEN1MAPTKMT2ANUDT1 | |
| SCHEMBL11595709 | 0.80 | AMY1A (0.44) | KDM4EMEN1MAPTKMT2ANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066562-A | ANTIOXIDANT | ETHYL CORPORATION (US) | 1978-01-03 | — | — | US | claimed |
| US-4066562-A | ANTIOXIDANT | ETHYL CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |