Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103438 | 0.89 | PARP1 (0.63) | PARP1POLBNPC1HDAC8HDAC6 | |
| SCHEMBL29365229 | 0.89 | PARP1 (0.63) | PARP1POLBNPC1HDAC8HDAC6 | |
| SCHEMBL2134942 | 0.89 | PBRM1 (0.61) | PARP1POLBNPC1MITFLMNA | |
| Hydrochloric Acid SCHEMBL10519739 | 0.87 | PBRM1 (0.59) | PARP1POLBNPC1MITFLMNA | |
| SCHEMBL9973084 | 0.85 | PBRM1 (0.69) | PARP1POLBNPC1MITFLMNA | |
| Benzoyl Chloride SCHEMBL10954201 | 0.83 | SMN1; SMN2 (0.59) | PARP1POLBNPC1HDAC8HDAC6 | |
| SCHEMBL28546583 | 0.83 | PBRM1 (0.53) | PARP1POLBNPC1MITFLMNA | |
| Benzoyl Chloride SCHEMBL8734541 | 0.81 | SMN1; SMN2 (0.56) | PARP1POLBNPC1HDAC8HDAC6 | |
| Phenol SCHEMBL28085177 | 0.77 | PBRM1 (0.58) | PARP1POLBNPC1MITFLMNA | |
| SCHEMBL29168864 | 0.77 | CYP3A4 (0.55) | POLBNPC1MITFLMNAPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |