Benzoyl Chloride

Benzoyl Chloride

SCHEMBL8734541

Cc1cccc(C)c1.O=C(Cl)c1ccccc1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.56
PARP1 P09874 1/20 0.53
POLB P06746 3/20 0.53
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
KCNK3 O14649 2/20 0.50
KCNK9 Q9NPC2 2/20 0.50
ACHE P22303 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
MAPT P10636 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
CNR2 P34972 2/20 0.47
CNR1 P21554 1/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KCNH2 Q12809 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoyl Chloride SCHEMBL10954201 0.94 SMN1; SMN2 (0.59) SMN1; SMN2PARP1POLBMEN1KMT2A
Benzoyl Chloride SCHEMBL28505141 0.91 CES2 (0.50) SMN1; SMN2PARP1POLBMEN1KMT2A
Benzoyl Chloride SCHEMBL27561425 0.89 CES2 (0.58) SMN1; SMN2PARP1POLBMEN1KMT2A
SCHEMBL29365229 0.87 PARP1 (0.63) SMN1; SMN2PARP1POLBMEN1KMT2A
SCHEMBL103438 0.87 PARP1 (0.63) SMN1; SMN2PARP1POLBMEN1KMT2A
Toluene SCHEMBL29163900 0.85 CES2 (0.58) SMN1; SMN2POLBMEN1KMT2AACHE
M-Xylene SCHEMBL31348956 0.84 ACHE (0.63) SMN1; SMN2PARP1POLBMEN1KMT2A
Toluene SCHEMBL29061412 0.83 TPMT (0.52) SMN1; SMN2PARP1POLBMEN1KMT2A
Benzoyl Chloride SCHEMBL29059235 0.83 CES2 (0.53) SMN1; SMN2POLBMEN1KMT2AMAPT
Benzoyl Chloride SCHEMBL1397148 0.83 CES2 (0.68) SMN1; SMN2POLBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0852582-A1 MODIFIED FLUOROSULFONIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-07-15 EP disclosed
WO-1997011081-A1 MODIFIED FLUOROSULFONIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-27 WO disclosed