Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614284 | 0.80 | TDP1 (0.53) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL11632618 | 0.78 | ALDH1A1 (0.41) | TDP1TSHRMAPTALDH1A1POLB | |
| SCHEMBL11483675 | 0.77 | MAPT (0.54) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL11962582 | 0.75 | TDP1 (0.50) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL1538922 | 0.75 | MAPT (0.56) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL3862471 | 0.74 | APEX1 (0.50) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL11124749 | 0.74 | TDP1 (0.49) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL3862467 | 0.74 | APEX1 (0.50) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL11633347 | 0.74 | TDP1 (0.49) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL11250876 | 0.74 | TDP1 (0.49) | TDP1TSHRMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080461-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4002640-A | ANTIFUNGAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-11 | — | — | US | disclosed |