SCHEMBL11629933

SCHEMBL11629933

CCCCN1CCN(C(=O)C(C)n2nc(Br)c(Br)c2Br)CC1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR183 P32249 1/20 0.40
HRH2 P25021 12/20 0.40
HRH1 P35367 12/20 0.40
CHRM3 P20309 1/20 0.38
GFER P55789 1/20 0.33
CYP2C19 P33261 1/20 0.33
POLB P06746 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11627637 0.80 ALDH1A1 (0.39) GFERUSP2
SCHEMBL11633888 0.79 ALDH1A1 (0.41) GFERPOLBUSP2
SCHEMBL11629136 0.79 ALDH1A1 (0.41) GFERPOLBUSP2
SCHEMBL11627905 0.77 GFER (0.34) GFER
SCHEMBL11626856 0.77 GAA (0.44) GFERCYP2C19
SCHEMBL20621097 0.75 HRH2 (0.55) GPR183HRH2HRH1CHRM3CYP2C19
SCHEMBL23572025 0.71 HRH2 (0.57) HRH2HRH1CHRM3CYP2C19POLB
SCHEMBL19710862 0.70 HRH2 (0.56) HRH2HRH1CHRM3CYP2C19POLB
SCHEMBL25509591 0.70 HRH2 (0.56) HRH2HRH1CHRM3CYP2C19POLB
SCHEMBL16435182 0.70 CYP2C19 (0.45) GPR183HRH2HRH1CHRM3CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4089672-A HERBICIDES THE UPJOHN COMPANY (US) 1978-05-16 US disclosed
US-4084955-A 1-CARBOXYALKYL-DI- AND TRIHALOPYRAZOLES, HERBICIDES THE UPJOHN COMPANY (US) 1978-04-18 US disclosed