Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629136 | 0.98 | ALDH1A1 (0.41) | ALDH1A1HTTHPGDGAAGFER | |
| SCHEMBL11633888 | 0.98 | ALDH1A1 (0.41) | ALDH1A1HTTHPGDGAAGFER | |
| SCHEMBL11626856 | 0.87 | GAA (0.44) | ALDH1A1HPGDGAAGFERSMN1; SMN2 | |
| SCHEMBL11627905 | 0.87 | GFER (0.34) | ALDH1A1HPGDGFERNPC1RAB9A | |
| SCHEMBL11826664 | 0.86 | RAB9A (0.45) | ALDH1A1HTTHPGDGAAGFER | |
| SCHEMBL11629933 | 0.80 | GPR183 (0.40) | GFERUSP2 | |
| SCHEMBL11630866 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1HTTHPGDNPC1SMN1; SMN2 | |
| SCHEMBL11627389 | 0.77 | PDE9A (0.36) | ALDH1A1HTTHPGDGAAKMT2A | |
| SCHEMBL11628948 | 0.77 | DPP4 (0.33) | NPC1RAB9A | |
| SCHEMBL11628708 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HTTHPGDRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4089672-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4084955-A | 1-CARBOXYALKYL-DI- AND TRIHALOPYRAZOLES, HERBICIDES | THE UPJOHN COMPANY (US) | 1978-04-18 | — | — | US | disclosed |