Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | HTR5A | P47898 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13131190 | 0.83 | DRD2 (0.56) | DRD2DRD4DRD3HTR5ADRD1 | |
| SCHEMBL13131189 | 0.83 | DRD2 (0.56) | DRD2DRD4DRD3HTR5ADRD1 | |
| SCHEMBL21471350 | 0.83 | DRD2 (0.56) | DRD2DRD4DRD3HTR5ADRD1 | |
| SCHEMBL11629630 | 0.83 | DRD2 (0.56) | DRD2DRD4DRD3HTR5ADRD1 | |
| SCHEMBL10164852 | 0.83 | PTGER4 (0.43) | DRD2DRD4DRD3HTR5ADRD1 | |
| Hydrochloric Acid SCHEMBL2816537 | 0.82 | ACHE (0.58) | DRD2DRD4DRD3HTR5ADRD1 | |
| Hydrochloric Acid SCHEMBL31186914 | 0.82 | ACHE (0.58) | DRD2DRD4DRD3HTR5ADRD1 | |
| Hydrochloric Acid SCHEMBL2816538 | 0.82 | ACHE (0.58) | DRD2DRD4DRD3HTR5ADRD1 | |
| Hydrochloric Acid SCHEMBL2817315 | 0.82 | ACHE (0.58) | DRD2DRD4DRD3HTR5ADRD1 | |
| SCHEMBL5666214 | 0.80 | DRD2 (0.42) | DRD2DRD4DRD3HTR5ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2014155301-A1 | SUBSTITUTED BICYCLIC COMPOUNDS AS INHIBITORS OF EZH2 | Piramal Enterprises Limited (IN) | 2014-10-02 | — | — | WO | disclosed |
| US-4111997-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY | TAKEDA CHEMICAL COMPANY, LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-4007225-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-02-08 | — | — | US | disclosed |
| US-3953500-A | ANTIPYRETICS, ANALGESICS, ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-27 | — | — | US | disclosed |