Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | PRCP | P42785 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL11632886 | 0.86 | KDM4E (0.59) | CHRM2CHRM1DRD3ALDH1A1KDM4E | |
| SCHEMBL11629076 | 0.81 | CHRM2 (0.44) | CHRM2CHRM1DRD3ALDH1A1KDM4E | |
| SCHEMBL11819075 | 0.73 | BCHE (0.40) | CHRM2CHRM1DRD3ALDH1A1KDM4E | |
| SCHEMBL7185401 | 0.73 | CHRM2 (0.78) | CHRM2CHRM1DRD3ALDH1A1KDM4E | |
| Citric Acid SCHEMBL11816888 | 0.70 | KDM4E (0.56) | CHRM2CHRM1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11817911 | 0.69 | GAA (0.44) | CHRM2ALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL11630675 | 0.68 | KDM4E (0.37) | CHRM2CHRM1DRD3ALDH1A1KDM4E | |
| SCHEMBL24486783 | 0.67 | CHRM2 (0.56) | CHRM2CHRM1DRD3ALDH1A1KDM4E | |
| SCHEMBL11631645 | 0.67 | ALDH1A1 (0.39) | CHRM2CHRM1DRD3ALDH1A1KDM4E | |
| SCHEMBL11630302 | 0.67 | ALDH1A1 (0.34) | ALDH1A1KDM4ELMNATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970672-A | 2,2 Disubstituted-benzodioxoles | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-07-20 | — | — | US | claimed |
| US-4091222-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANALGESIC, ANTITUSSIVE, CNS EFFECTS, ANAESTHETICS, ANTIARRHYTHMIC, HYPOTENSIVE, ANTICOAGULANTS | MANGHISI ELSO | 1978-05-23 | — | — | US | disclosed |
| US-3970672-A | 2,2 Disubstituted-benzodioxoles | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-07-20 | — | — | US | disclosed |