Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL11632888 | 0.85 | KDM4E (0.41) | ALDH1A1MAPTKDM4EGAAAPEX1 | |
| SCHEMBL11629078 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4EGAAAPEX1 | |
| SCHEMBL11815714 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EGAAAPEX1 | |
| SCHEMBL11820267 | 0.70 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EGAAAPEX1 | |
| SCHEMBL11819088 | 0.68 | KDM4E (0.31) | ALDH1A1MAPTKDM4EAPEX1 | |
| SCHEMBL11630299 | 0.67 | CHRM2 (0.50) | ALDH1A1KDM4ESMN1; SMN2LMNATDP1 | |
| SCHEMBL14779113 | 0.65 | TSHR (0.47) | ALDH1A1KDM4EAPEX1SMN1; SMN2TDP1 | |
| SCHEMBL11814793 | 0.65 | EGFR (0.33) | ALDH1A1MAPTSMN1; SMN2TDP1HSP90AA1 | |
| SCHEMBL14559519 | 0.65 | GRIN1 (0.43) | APEX1SMN1; SMN2TDP1GRIN1GRIN2A | |
| SCHEMBL11630680 | 0.65 | ALDH1A1 (0.30) | ALDH1A1GAALMNAHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970672-A | 2,2 Disubstituted-benzodioxoles | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-07-20 | — | — | US | claimed |
| US-4091222-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANALGESIC, ANTITUSSIVE, CNS EFFECTS, ANAESTHETICS, ANTIARRHYTHMIC, HYPOTENSIVE, ANTICOAGULANTS | MANGHISI ELSO | 1978-05-23 | — | — | US | disclosed |
| US-3970672-A | 2,2 Disubstituted-benzodioxoles | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-07-20 | — | — | US | disclosed |