Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 10/20 | 0.49 |
| ▸ | RAB9A | P51151 | 10/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943611 | 0.80 | MEN1 (0.50) | TSHRNPC1RAB9AMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9617121 | 0.79 | MEN1 (0.49) | TSHRNPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL17504830 | 0.77 | MAPT (0.54) | TSHRNPC1RAB9AGAAMAPT | |
| SCHEMBL15599673 | 0.77 | MAPT (0.54) | TSHRNPC1RAB9AGAAMAPT | |
| SCHEMBL8125712 | 0.76 | ALDH1A1 (0.47) | TSHRNPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL17008170 | 0.75 | POLB (0.52) | TSHRNPC1RAB9AGAAMAPT | |
| SCHEMBL8116755 | 0.75 | TSHR (0.49) | TSHRNPC1RAB9AGAAMAPT | |
| SCHEMBL14347349 | 0.74 | TSHR (0.47) | TSHRRAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL14374719 | 0.74 | ATM (0.55) | TSHRNPC1RAB9AGAAMAPT | |
| SCHEMBL11466936 | 0.72 | TSHR (0.54) | TSHRNPC1RAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4031093-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |