Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17504830 | 1.00 | MAPT (0.54) | MAPTPOLBCYP2C19TSHRL3MBTL1 | |
| SCHEMBL17008170 | 0.84 | POLB (0.52) | MAPTPOLBCYP2C19TSHRL3MBTL1 | |
| SCHEMBL6794012 | 0.77 | HDAC3 (0.48) | CYP2C19TSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL6794018 | 0.77 | HDAC3 (0.48) | CYP2C19TSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL11630477 | 0.77 | TSHR (0.50) | MAPTPOLBCYP2C19TSHRL3MBTL1 | |
| SCHEMBL11123905 | 0.76 | NPC1 (0.60) | MAPTPOLBCYP2C19TSHRL3MBTL1 | |
| SCHEMBL6649650 | 0.76 | POLB (0.49) | MAPTPOLBCYP2C19TSHRL3MBTL1 | |
| SCHEMBL6791698 | 0.76 | POLB (0.49) | MAPTPOLBCYP2C19TSHRL3MBTL1 | |
| SCHEMBL13165822 | 0.76 | TNF (0.58) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL13165824 | 0.76 | TNF (0.58) | MAPTPOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014041559-A2 | PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE AND INTERMEDIATES THEREOF | GLENMARK PHARMACEUTICALS LIMITED; GLENMARK GENERICS LIMITED (IN) | 2014-03-20 | — | — | WO | disclosed |