Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628940 | 0.89 | LMNA (0.42) | HCRTR1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL11630789 | 0.88 | LMNA (0.48) | ALDH1A1HSD17B10L3MBTL1MAPTMAPK1 | |
| SCHEMBL11633426 | 0.88 | HCRTR1 (0.48) | HCRTR1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL11629846 | 0.84 | RIPK1 (0.43) | ALDH1A1HPGDHSD17B10TSHRMEN1 | |
| SCHEMBL4696206 | 0.81 | TSHR (0.46) | ALDH1A1HSD17B10L3MBTL1MAPTGAA | |
| SCHEMBL10668614 | 0.81 | MAPT (0.47) | ALDH1A1HPGDL3MBTL1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4693594 | 0.79 | MAPT (0.46) | ALDH1A1HPGDL3MBTL1KDM4EMAPT | |
| SCHEMBL11242713 | 0.78 | TSHR (0.43) | ALDH1A1HPGDHSD17B10MAPTTSHR | |
| SCHEMBL973270 | 0.77 | HCRTR1 (0.54) | HCRTR1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4673662 | 0.75 | IRAK4 (0.50) | ALDH1A1HSD17B10KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4031093-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |