Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485068 | 0.90 | ALDH1A1 (0.56) | LMNAALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL11485703 | 0.89 | L3MBTL1 (0.55) | LMNAALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL11635310 | 0.86 | ALDH1A1 (0.53) | LMNAALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL11633900 | 0.83 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1GAAKDM4EHPGD | |
| SCHEMBL9511582 | 0.81 | ALDH1A1 (0.56) | LMNAALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL9510364 | 0.80 | ALDH1A1 (0.53) | LMNAALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL11493819 | 0.77 | GAA (0.65) | LMNAALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL11499032 | 0.77 | KDM4E (0.53) | LMNAALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL11483590 | 0.76 | GAA (0.64) | LMNAALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL11631534 | 0.76 | GAA (0.64) | LMNAALDH1A1L3MBTL1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087606-A | ANTIALLERGENS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-05-02 | — | — | US | disclosed |
| US-4054591-A | ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |