Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628094 | 0.89 | POLB (0.40) | ALDH1A1HTTSMN1; SMN2POLBABCB1 | |
| SCHEMBL11627980 | 0.81 | MEN1 (0.42) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11632204 | 0.77 | MEN1 (0.38) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL29921398 | 0.76 | HTR1A (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL29921104 | 0.76 | HTR1A (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL14615145 | 0.73 | KMT2A (0.47) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6300033 | 0.73 | MAPT (0.49) | HTTSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL4776765 | 0.72 | MEN1 (0.52) | ALDH1A1MEN1KMT2AKDM4CTDP1 | |
| SCHEMBL29920999 | 0.72 | LMNA (0.46) | HTTMEN1KMT2A | |
| SCHEMBL11515511 | 0.71 | MEN1 (0.34) | MEN1KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | disclosed |