Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632049 | 0.87 | POLB (0.44) | GSTO1POLBHSD17B10KDM4EMAPT | |
| SCHEMBL10962880 | 0.85 | GSTO1 (0.62) | GSTO1POLBHSD17B10KDM4EMAPT | |
| SCHEMBL11632513 | 0.85 | POLB (0.49) | GSTO1ALDH1A1TP53POLBHSD17B10 | |
| SCHEMBL11930743 | 0.84 | POLB (0.62) | POLBHSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11597826 | 0.83 | POLB (0.51) | GSTO1ALDH1A1POLBHSD17B10KDM4E | |
| SCHEMBL11595388 | 0.80 | GSTO1 (0.50) | GSTO1ALDH1A1TP53POLBHSD17B10 | |
| SCHEMBL11780405 | 0.79 | GSK3B (0.48) | ALDH1A1HIF1ARAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11531237 | 0.77 | CA1 (0.62) | RAB9ACA1CA2 | |
| SCHEMBL11183264 | 0.77 | GSTO1 (0.60) | GSTO1ALDH1A1POLBRAB9AKMT2A | |
| SCHEMBL15650972 | 0.76 | TSHR (0.56) | GSTO1ALDH1A1POLBHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083979-A | Thiazolidine derivatives and their use as salidiuretics | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |