Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962880 | 0.85 | GSTO1 (0.62) | POLBSMN1; SMN2KDM4EKMT2AGSTO1 | |
| SCHEMBL11595561 | 0.84 | POLB (0.62) | POLBSMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL11595632 | 0.84 | POLB (0.54) | POLBSMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL11632306 | 0.83 | GSTO1 (0.46) | POLBSMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL11595388 | 0.82 | GSTO1 (0.50) | POLBSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11780405 | 0.79 | GSK3B (0.48) | SMN1; SMN2KMT2AALDH1A1TDP1CYP1A2 | |
| SCHEMBL11596906 | 0.78 | LMNA (0.55) | POLBKMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL11531237 | 0.77 | CA1 (0.62) | CA1CA2 | |
| SCHEMBL11183264 | 0.77 | GSTO1 (0.60) | POLBSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL13545186 | 0.77 | GSTO1 (0.55) | POLBSMN1; SMN2KDM4EKMT2AGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |