Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633443 | 0.84 | SMN1; SMN2 (0.45) | ATMKMT2AMEN1GRIN2DGRIN3B | |
| SCHEMBL11635348 | 0.82 | SMN1; SMN2 (0.47) | HSD11B1EPHX2ATMKMT2AMEN1 | |
| SCHEMBL11635875 | 0.79 | KDM4E (0.50) | EPHX2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL31288968 | 0.69 | MEN1 (0.44) | HSD11B1EPHX2ATMKMT2AMEN1 | |
| SCHEMBL6313788 | 0.68 | KDM4E (0.58) | HSD11B1EPHX2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5252707 | 0.68 | GRIN2D (0.46) | ATMKMT2AMEN1GRIN2DGRIN3B | |
| SCHEMBL28350293 | 0.67 | GRIN2D (0.41) | EPHX2ATMKMT2AMEN1GRIN2D | |
| SCHEMBL2551138 | 0.66 | KDM4E (0.37) | KMT2AMEN1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL13419180 | 0.66 | KDM4E (0.37) | KMT2AMEN1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL3534793 | 0.66 | KDM4E (0.37) | KMT2AMEN1SIGMAR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100170-A | ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE INHIBITORS | PENNWALT CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |