Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633443 | 0.84 | SMN1; SMN2 (0.45) | KDM4EKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL11635348 | 0.82 | SMN1; SMN2 (0.47) | KDM4EKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL11633407 | 0.79 | HSD11B1 (0.38) | KDM4EKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL24352139 | 0.68 | KDM4E (0.96) | KDM4EKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL5252707 | 0.68 | GRIN2D (0.46) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL12216277 | 0.68 | KDM4E (0.62) | KDM4EKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL2529272 | 0.68 | KDM4E (0.62) | KDM4EKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL4203286 | 0.67 | MAPK1 (0.47) | KMT2AMEN1ALDH1A1MAPK1EPHX2 | |
| SCHEMBL643674 | 0.66 | KMT2A (0.42) | KDM4EKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL21564194 | 0.66 | KMT2A (0.42) | KDM4EKMT2AMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100170-A | ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE INHIBITORS | PENNWALT CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |