Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633443 | 0.98 | SMN1; SMN2 (0.45) | SMN1; SMN2BPTFKMT2AMEN1POLB | |
| SCHEMBL11633407 | 0.82 | HSD11B1 (0.38) | SMN1; SMN2BPTFKMT2AMEN1ALDH1A1 | |
| SCHEMBL11635875 | 0.82 | KDM4E (0.50) | KMT2AMEN1TSHRALDH1A1PKM | |
| SCHEMBL5252707 | 0.71 | GRIN2D (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1GRIN2D | |
| SCHEMBL27565285 | 0.67 | CYP3A4 (0.39) | SMN1; SMN2KMT2AMEN1POLBTDP1 | |
| SCHEMBL3511589 | 0.67 | SLC22A2 (0.50) | SMN1; SMN2KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL5306258 | 0.67 | GRIN2D (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1GRIN2D | |
| SCHEMBL28350293 | 0.66 | GRIN2D (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1GRIN2D | |
| Hydrochloric Acid SCHEMBL11637716 | 0.66 | MAPT (0.52) | SMN1; SMN2KMT2AMEN1POLBTSHR | |
| SCHEMBL23869469 | 0.65 | CYP3A4 (0.38) | SMN1; SMN2KMT2AMEN1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100170-A | ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE INHIBITORS | PENNWALT CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |