Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 5/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 4/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 2/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453419 | 0.85 | STS (0.45) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL19735281 | 0.84 | CSNK1D (0.49) | CSNK1DCSNK1G2KIF11L3MBTL1G6PD | |
| SCHEMBL24617017 | 0.84 | CSNK1D (0.49) | CSNK1DCSNK1G2KIF11L3MBTL1G6PD | |
| SCHEMBL28456601 | 0.82 | G6PD (0.47) | KDM4ETDP1G6PDSTSMIF | |
| SCHEMBL28462335 | 0.79 | STS (0.49) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL11632495 | 0.78 | CYP2A6 (0.44) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7719779 | 0.78 | KDM4E (0.58) | KIF11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL11631827 | 0.78 | KDM4E (0.50) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL30227432 | 0.78 | KDM4E (0.58) | KIF11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL11633430 | 0.76 | KIF11 (0.51) | KIF11NPC1RAB9ATDP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103015-A | TRICYCLIC THIOXANTHONE-10,10-DIOXIDES | BURROUGHS WELLCOME CO. (US) | 1978-07-25 | — | — | US | disclosed |