Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAAO | P46952 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635261 | 0.85 | ALDH1A1 (0.40) | HAAOALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11635537 | 0.81 | PRSS1 (0.42) | HAAOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11637223 | 0.80 | CNR2 (0.45) | HAAOALDH1A1MEN1KMT2ANR4A1 | |
| SCHEMBL11637352 | 0.77 | KDM4E (0.43) | HAAOALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL11637801 | 0.77 | KDM4E (0.43) | HAAOALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL11639242 | 0.76 | HAAO (0.43) | HAAOALDH1A1MEN1KMT2ANR4A1 | |
| SCHEMBL11637724 | 0.76 | ALDH1A1 (0.45) | HAAOALDH1A1MEN1KMT2ANR4A1 | |
| SCHEMBL7337363 | 0.71 | HAAO (0.49) | HAAOALDH1A1MEN1KMT2ANR4A1 | |
| SCHEMBL11665008 | 0.68 | KMT2A (0.44) | HAAOALDH1A1MEN1KMT2ANR4A1 | |
| Phthalic Acid SCHEMBL7129666 | 0.67 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108630-A | 1-Alkylpyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4038065-A | 1-ALKYLPYRID-2-ONE | ROHM AND HAAS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |