Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637801 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11637223 | 0.94 | CNR2 (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11639242 | 0.87 | HAAO (0.43) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL11635537 | 0.80 | PRSS1 (0.42) | ALDH1A1PPARAMAPTRARBNPSR1 | |
| SCHEMBL11633730 | 0.77 | HAAO (0.39) | KDM4EALDH1A1GAAPPARAMAPT | |
| SCHEMBL11637724 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1GAAMAPTCNR2 | |
| SCHEMBL11635261 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL23751998 | 0.76 | TLR8 (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL14958645 | 0.76 | TLR8 (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL14958647 | 0.76 | TLR8 (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108630-A | 1-Alkylpyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4038065-A | 1-ALKYLPYRID-2-ONE | ROHM AND HAAS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |