Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403615 | 0.84 | CYP2C19 (0.59) | MAPTPOLBMAPK1KMT2AMEN1 | |
| SCHEMBL30232741 | 0.84 | CYP2C19 (0.59) | MAPTPOLBMAPK1KMT2AMEN1 | |
| SCHEMBL11632125 | 0.83 | P4HTM (0.56) | MAPTPOLBKMT2AMEN1CYP2C19 | |
| SCHEMBL11632758 | 0.83 | P4HTM (0.56) | MAPTPOLBKMT2AMEN1CYP2C19 | |
| SCHEMBL11632984 | 0.81 | MAPK1 (0.54) | MAPTPOLBMAPK1PARP1L3MBTL1 | |
| SCHEMBL11630275 | 0.81 | MAPK1 (0.54) | MAPK1PARP1L3MBTL1P4HTM | |
| SCHEMBL753810 | 0.80 | MAPK1 (0.53) | MAPTPOLBMAPK1PARP1KMT2A | |
| SCHEMBL4285254 | 0.80 | MAPK1 (0.53) | POLBMAPK1PARP1CYP2C19L3MBTL1 | |
| SCHEMBL11635977 | 0.80 | MAPK1 (0.53) | MAPTMAPK1PARP1KMT2AMEN1 | |
| SCHEMBL6014107 | 0.80 | MEN1 (0.51) | MAPTPOLBMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4109000-A | HYPOTENSIVES | NIPPON SHINYAKU CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |