SCHEMBL753810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11632984	0.86	MAPK1 (0.54)	MAPK1PARP1P4HTMMAPTKDM4E
	SCHEMBL11630275	0.86	MAPK1 (0.54)	MAPK1PARP1P4HTMKDM4EL3MBTL1
	SCHEMBL27686080	0.85	MAPT (0.49)	MAPTKDM4EMEN1KMT2ANPSR1
	SCHEMBL4285254	0.85	MAPK1 (0.53)	MAPK1PARP1KDM4EL3MBTL1LTA4H
	SCHEMBL11635977	0.85	MAPK1 (0.53)	MAPK1PARP1P4HTMMAPTKDM4E
	SCHEMBL9938469	0.85	MAPK1 (0.50)	MAPK1PARP1MAPTKDM4EL3MBTL1
	SCHEMBL21384222	0.84	MAPK1 (0.49)	MAPK1PARP1MAPTKDM4EL3MBTL1
	SCHEMBL755141	0.83	MAPT (0.46)	MAPK1MAPTKDM4EL3MBTL1MEN1
	SCHEMBL21384012	0.83	PARP1 (0.45)	MAPK1PARP1MAPTKDM4EL3MBTL1
	SCHEMBL29614576	0.82	MAPK1 (0.65)	MAPK1P4HTMMAPTKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.