Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636106 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL11635995 | 0.78 | BCL2L1 (0.37) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL11635413 | 0.75 | NPC1 (0.43) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL11636498 | 0.73 | POLB (0.42) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL11610725 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2ALMNATSHR | |
| SCHEMBL11637797 | 0.71 | KDM4E (0.77) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL2212267 | 0.71 | KDM4E (0.40) | ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7883039 | 0.71 | CYP1A2 (0.33) | KDM4EKMT2AMAPTMEN1THRB | |
| SCHEMBL30521348 | 0.70 | SMN1; SMN2 (0.35) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL7888426 | 0.69 | GRIN2D (0.41) | KDM4EMAPTLMNANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108630-A | 1-Alkylpyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4038065-A | 1-ALKYLPYRID-2-ONE | ROHM AND HAAS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |