Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266944 | 0.89 | BCL2L1 (0.38) | BCL2L1KDM4ECA2CA1MAPT | |
| SCHEMBL11637786 | 0.89 | BCL2L1 (0.37) | BCL2L1KDM4ECA2MAPTTP53 | |
| SCHEMBL11636904 | 0.86 | TP53 (0.38) | BCL2L1KDM4ECA2CA1MAPT | |
| SCHEMBL11633973 | 0.78 | ALDH1A1 (0.46) | KDM4EMAPTALDH1A1HSD17B10TSHR | |
| SCHEMBL11635413 | 0.78 | NPC1 (0.43) | KDM4EMAPTALDH1A1MAPK1LMNA | |
| SCHEMBL11637890 | 0.77 | KDM4E (0.59) | KDM4EMAPTALDH1A1MAPK1HSD17B10 | |
| SCHEMBL4271188 | 0.72 | BCL2L1 (0.38) | BCL2L1TP53LMNASMN1; SMN2 | |
| SCHEMBL11635261 | 0.72 | ALDH1A1 (0.40) | KDM4ECA2MAPTTP53ALDH1A1 | |
| SCHEMBL11241059 | 0.71 | BCL2L1 (0.37) | BCL2L1KDM4ECA2MAPTTP53 | |
| SCHEMBL9347629 | 0.70 | CNR2 (0.46) | KDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108630-A | 1-Alkylpyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4038065-A | 1-ALKYLPYRID-2-ONE | ROHM AND HAAS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |