Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAT2A | P31153 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ESRRB | O95718 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807689 | 0.87 | KDM4E (0.59) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13585102 | 0.77 | KDM4E (0.62) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9266044 | 0.75 | KDM4E (0.44) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22750952 | 0.74 | KDM4E (0.66) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL31663132 | 0.72 | MPO (0.51) | HSP90AB1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL13726642 | 0.71 | MAPT (0.58) | HSP90AB1MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL24108945 | 0.71 | POLB (0.56) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL13726180 | 0.71 | KDM4E (0.52) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL26314747 | 0.71 | KDM4E (0.55) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL24108921 | 0.71 | MAPT (0.61) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083948-A | IODINE LABELS | HOFFMANN-LA ROCHE, INC. (US) | 1978-04-11 | — | — | US | disclosed |