Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637871 | 0.83 | HRH3 (0.36) | HRH3KDM2BHTR2B | |
| SCHEMBL11632635 | 0.76 | HRH3 (0.38) | HRH3SMN1; SMN2KDM2BPKMCHRM2 | |
| SCHEMBL11634087 | 0.72 | HRH3 (0.40) | HRH3SMN1; SMN2CHRM2HTR1ADRD3 | |
| SCHEMBL16370596 | 0.70 | SMN1; SMN2 (0.51) | HRH3SMN1; SMN2DRD3ALDH1A1POLB | |
| SCHEMBL23114668 | 0.66 | HRH3 (0.39) | HRH3CHRM2HTR1ADRD3HTR2B | |
| SCHEMBL23108965 | 0.66 | HRH3 (0.39) | HRH3CHRM2HTR1ADRD3HTR2B | |
| SCHEMBL23104062 | 0.66 | HRH3 (0.39) | HRH3CHRM2HTR1ADRD3HTR2B | |
| SCHEMBL14075675 | 0.66 | SMN1; SMN2 (0.46) | SMN1; SMN2DRD3ALDH1A1POLBMAPT | |
| SCHEMBL23104057 | 0.66 | HRH3 (0.39) | HRH3CHRM2HTR1ADRD3HTR2B | |
| SCHEMBL23104055 | 0.66 | HRH3 (0.39) | HRH3CHRM2HTR1ADRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4109088-A | ANTIDEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |