Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370718 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ALMNAPOLB | |
| SCHEMBL16371130 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AALOX15TSHR | |
| Hydrochloric Acid SCHEMBL16371043 | 0.79 | FKBP1A (0.49) | SMN1; SMN2MEN1KMT2ALMNAPOLB | |
| SCHEMBL16370936 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AHRH3LMNA | |
| SCHEMBL16370882 | 0.78 | CYP1A2 (0.47) | MEN1KMT2AALOX15HSD17B10MAPK1 | |
| SCHEMBL16370623 | 0.78 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL16371037 | 0.76 | KMT2A (0.51) | SMN1; SMN2MEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL16473527 | 0.70 | TSHR (0.50) | SMN1; SMN2KMT2AALOX15TSHRHSD17B10 | |
| SCHEMBL11635461 | 0.70 | HRH3 (0.41) | SMN1; SMN2HRH3POLBALDH1A1MAPT | |
| SCHEMBL6832889 | 0.69 | CHRNB2 (0.39) | MEN1KMT2ATSHRHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | claimed |
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | disclosed |