Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635461 | 0.83 | HRH3 (0.41) | HRH3HTR2BKDM2B | |
| SCHEMBL11634298 | 0.74 | HRH3 (0.38) | HRH3HTR2B | |
| SCHEMBL11629586 | 0.65 | ACHE (0.36) | MTNR1BMTNR1ANQO2ACHE | |
| SCHEMBL13306290 | 0.64 | HTR2C (0.66) | MTNR1BMTNR1AHTR2AHTR2CHTR2B | |
| SCHEMBL13306294 | 0.64 | HTR2C (0.66) | MTNR1BMTNR1AHTR2AHTR2CHTR2B | |
| SCHEMBL12593301 | 0.64 | HTR2C (0.66) | MTNR1BMTNR1AHTR2AHTR2CHTR2B | |
| SCHEMBL14374374 | 0.64 | ACHE (0.50) | MTNR1AACHE | |
| SCHEMBL23104057 | 0.64 | HRH3 (0.39) | HRH3HTR2B | |
| SCHEMBL23114668 | 0.64 | HRH3 (0.39) | HRH3HTR2B | |
| SCHEMBL23104062 | 0.64 | HRH3 (0.39) | HRH3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4109088-A | ANTIDEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |