SCHEMBL11635902

SCHEMBL11635902

CCCNc1c(F)nnc(Cl)c1Cl

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22049121 0.67
SCHEMBL9689891 0.67 BPTF (0.33) PDE10AKMT2A
Hydrochloric Acid SCHEMBL20572122 0.65
SCHEMBL7182685 0.64 MEN1 (0.42) KMT2AMEN1MAPTHTT
SCHEMBL11534893 0.62
SCHEMBL11537902 0.61
SCHEMBL31425701 0.61
SCHEMBL13947538 0.58 MAPK1 (0.41) PDE10AKMT2AMEN1MAPTHTT
SCHEMBL1440326 0.58 ALDH1A1 (0.45) PDE10AKMT2AMEN1MAPTHTT
SCHEMBL11638624 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4083713-A CONTROLLING WEEDS ROHM AND HAAS COMPANY (US) 1978-04-11 US disclosed