SCHEMBL7182685

SCHEMBL7182685

CCCNc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX12 P18054 1/20 0.42
CYP2C19 P33261 1/20 0.42
RAB9A P51151 1/20 0.42
HTT P42858 1/20 0.41
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
GAA P10253 2/20 0.31
KDM4E B2RXH2 2/20 0.30
LMNA P02545 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29123790 0.87 CA1 (0.41) MEN1MAPTKMT2ANPC1ALDH1A1
SCHEMBL6285606 0.82 MAPT (0.46) MEN1MAPTKMT2AALDH1A1HTT
SCHEMBL27552289 0.80 KMT2A (0.45) MEN1MAPTKMT2AALDH1A1HTT
SCHEMBL28988343 0.79 MAPK1 (0.50) MEN1MAPTKMT2ANPC1ALDH1A1
SCHEMBL7689193 0.77 MAPT (0.64) MEN1MAPTKMT2AALDH1A1HTT
Iodide SCHEMBL29195564 0.74 TSHR (0.32) MEN1MAPTKMT2AALDH1A1HTT
SCHEMBL19121210 0.70 TRPA1 (0.44) MEN1MAPTKMT2ANPC1ALDH1A1
SCHEMBL25650262 0.70 RAPGEF4 (0.41) MEN1MAPTKMT2ANPC1ALDH1A1
SCHEMBL16790696 0.69 TRPA1 (0.43) MEN1MAPTKMT2ANPC1ALDH1A1
SCHEMBL13918748 0.69 GAA (0.41) MAPTALDH1A1MAPK1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016183101-A1 PALLADIUM-CATALYZED ARYLATION OF FLUOROALKYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-11-17 WO disclosed
US-20150211006-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2015-07-30 US disclosed
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150211006-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 MEN1 2026/4885MAPT 3098/4885KMT2A 2211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.